
Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug
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A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation
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This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate
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The internationally best-selling Medical Pharmacology at a Glance is the ideal companion for all medical and healthcare students, providing a visual overview of pharmacology, and describing the basic principles of drug action, interaction, absorption, and excretion. Clear and accessible chapters
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The internationally best-selling Medical Pharmacology at a Glance is the ideal companion for all medical and healthcare students, providing a visual overview of pharmacology, and describing the basic principles of drug action, interaction, absorption, and excretion. Clear and accessible chapters
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Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the «right» drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug
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Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new
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This comprehensive resource covers the fundamentals, formulation, and biopharmaceutical issues of lipid-based drug delivery. It presents the principles of lipid absorption and covers formulation issues, such as dissolution testing and stability testing, and physiological and biopharmaceutical
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The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten. In 21 chapters readers can benefit from the key working knowledge of today's leading pharmaceutical companies, including Pfizer,
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In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics
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Born in a prison and removed from his drug-dependent mother, rejection is all that 7-year-old Alex knows.When Cathy is asked to foster little Alex, aged 7, her immediate reaction is: Why can’t he stay with his present carers for the last month? He’s already had many moves since coming into care as
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Born in a prison and removed from his drug-dependent mother, rejection is all that 7-year-old Alex knows.When Cathy is asked to foster little Alex, aged 7, her immediate reaction is: Why can’t he stay with his present carers for the last month? He’s already had many moves since coming into care as
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