David Machin The Design of Studies for Medical Research
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The same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development. With the emphasis that is now placed on evidence-based medicine, such care and rigour will
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David Machin Sample Size Tables for Clinical Studies
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This book provides statisticians and researchers with the statistical tools – equations, formulae and numerical tables – to design and plan clinical studies and carry out accurate, reliable and reproducible analysis of the data so obtained. There is no way around this as incorrect procedure in
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David Machin Quality of Life
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The assessment of patient reported outcomes and health-related quality of life continue to be rapidly evolving areas of research and this new edition reflects the development within the field from an emerging subject to one that is an essential part of the assessment of clinical trials and other
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David Machin Quality of Life
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Quality of life studies form an essential part of the evaluation of any treatment. Written by two authors who are well respected within this field, Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported Outcomes, Second Edition lays down guidelines on assessing, analysing
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David Machin Textbook of Clinical Trials
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Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: «… very useful as an introduction to clinical research, or for those planning specific
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Dieter Hauschke Bioequivalence Studies in Drug Development
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Studies in bioequivalence are the commonly accepted method to demonstrate therapeutic equivalence between two medicinal products. Savings in time and cost are substantial when using bioequivalence as an established surrogate marker of therapeutic equivalence. For this reason the design, performance
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ECCS – European Convention for Constructional Steelwork Design of Steel Structures for Buildings in Seismic Areas. Eurocode 8: Design of Structures for Earthquake Resistance. Part 1: General Rules, Seismic Action and Rules for Buildings
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This volume elucidates the design criteria and principles for steel structures under seismic loads according to Eurocode 8-1. Worked Examples illustrate the application of the design rules. Two case studies serve as best-practice samples.
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Henrik Holbech Statistical Analysis of Ecotoxicity Studies
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A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess
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Ariane Auquier Statistical Methods for Comparative Studies
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Brings together techniques for the design and analysis of comparative studies. Methods include multivariate matching, standardization and stratification, analysis of covariance, logit analysis, and log linear analysis. Quantitatively assesses techniques' effectiveness in reducing bias. Discusses
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Mark Horstemeyer F. Integrated Computational Materials Engineering (ICME) for Metals
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Focuses entirely on demystifying the field and subject of ICME and provides step-by-step guidance on its industrial application via case studies This highly-anticipated follow-up to Mark F. Horstemeyer’s pedagogical book on Integrated Computational Materials Engineering (ICME) concepts includes
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Allan Hackshaw A Concise Guide to Observational Studies in Healthcare
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A Concise Guide to Observational Studies in Healthcare provides busy healthcare professionals with an easy-to-read introduction and overview to conducting, analysing and assessing observational studies. It is a suitable introduction for anyone without prior knowledge of study design, analysis or
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Juan A. Conesa Chemical Reactor Design
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A guide to the technical and calculation problems of chemical reactor analysis, scale-up, catalytic and biochemical reactor design Chemical Reactor Design offers a guide to the myriad aspects of reactor design including the use of numerical methods for solving engineering problems. The author – a
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