Hugo Kubinyi Nuclear Receptors as Drug Targets
Купить за 26693.37 RUR
Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and reference systematically treats the drug development aspects of all human nuclear receptors, including recently characterized receptors such as PPAR, FXR and
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Hugo Kubinyi G Protein-Coupled Receptors as Drug Targets
Купить за 25216.16 RUR
With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an important biological process that has not yet been covered in such depth in any other existing books on GPCRs. The international team of highly distinguished
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Hugo Kubinyi Transporters as Drug Carriers
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This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and
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Hugo Kubinyi Drug Bioavailability
Купить за 18011.54 RUR
The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane
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Hugo Kubinyi Voltage-Gated Ion Channels as Drug Targets
Купить за 26358.03 RUR
Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the
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Hugo Kubinyi Molecular Drug Properties
Купить за 24845.44 RUR
This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug
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Wen Xie Nuclear Receptors in Drug Metabolism
Купить за 12377.16 RUR
This book gives you an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development and equips you with the interdisciplinary understanding of these receptors and how they can be regulated. Pharmaceutical researchers will find this extremely useful in developing
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Hugo Kubinyi BioNMR in Drug Research
Купить за 23368.82 RUR
The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wuthrich. Edited by a former coworker of Wuthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining
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Hugo Kubinyi Chemoinformatics in Drug Discovery
Купить за 29180.92 RUR
This handbook provides the first-ever inside view of today's integrated approach to rational drug design. Chemoinformatics experts from large pharmaceutical companies, as well as from chemoinformatics service providers and from academia demonstrate what can be achieved today by harnessing the power
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Hugo Kubinyi Proteomics in Drug Research
Купить за 24853.37 RUR
From skillful handling of the wide range of technologies to successful applications in drug discovery – this handbook has all the information professional proteomics users need. Edited by experts working at one of the hot spots in European proteomic research, the numerous contributions by experts
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Hugo Kubinyi Chirality in Drug Research
Купить за 24853.37 RUR
Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals. The two editors from academia and a major pharmaceutical company have
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Hugo Kubinyi Protein Crystallography in Drug Discovery
Купить за 20091.78 RUR
The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structures of target proteins is more often than not the basis for an entire drug development program. Protein structures suited for rational drug design are
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