Tim Storr Ligand Design in Medicinal Inorganic Chemistry
Купить за 15598.8 RUR
Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease
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Группа авторов Ligand Design in Metal Chemistry
Купить за 14592.75 RUR
The design of ancillary ligands used to modify the structural and reactivity properties of metal complexes has evolved into a rapidly expanding sub-discipline in inorganic and organometallic chemistry. Ancillary ligand design has figured directly in the discovery of new bonding motifs and
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Arun K. Ghosh Structure-based Design of Drugs and Other Bioactive Molecules
Купить за 11106.05 RUR
Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide
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Hugo Kubinyi Structure-based Ligand Design
Купить за 17699.9 RUR
Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of structure-based ligand design. Although this method first emerged in the 1980s, it has already become a powerful tool for pharmaceutical
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Andrea Bellelli Reversible Ligand Binding
Купить за 10339.42 RUR
Presents the physical background of ligand binding and instructs on how experiments should be designed and analyzed Reversible Ligand Binding: Theory and Experiment discusses the physical background of protein-ligand interactions—providing a comprehensive view of the various biochemical
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Hugo Kubinyi Fragment-based Approaches in Drug Discovery
Купить за 26047.46 RUR
This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers
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Didier Rognan Ligand Design for G Protein-coupled Receptors
Купить за 23618.31 RUR
G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a rational drug design. Based on recent examples
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Peter Storr Get that Job in 7 simple steps
Купить за 188.16 RUR
7 simple steps to help you find your perfect jobKickstart your job applications and get the job you want. If you’re new to the job market, back for a restart, or want a change of scene, we’ll help you target what you want and show you how to get there.The job market is tougher than ever, and making
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Группа авторов De novo Molecular Design
Купить за 15262.43 RUR
Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules. A leader in the field and one of the
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Hugo Kubinyi Pharmacophores and Pharmacophore Searches
Купить за 20782.55 RUR
This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research. Starting with an introductory historical overview, the authors move on to
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Raimund Mannhold Drug Selectivity. An Evolving Concept in Medicinal Chemistry
Купить за 22977.36 RUR
The book «Drug Selectivity – An Evolving Concept in Medicinal Chemistry» provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and
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Raimund Mannhold Drug Selectivity
Купить за 19613.41 RUR
The book «Drug Selectivity – An Evolving Concept in Medicinal Chemistry» provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and
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